Introduction
Over 30% of food is lost, around 25% of vaccines are
wasted, and pandemic surveillance systems still face significant challenges,
due to inadequate management strategies such as broken cold-chain
systems.
The cold chain is a temperature-controlled supply system essential for preserving food, vaccines, reagents, and biological samples, playing a critical role in health outcomes and food security. It also intersects with climate change due to its reliance on energy and refrigerants.
In low- and middle-income countries (LMICs), cold-chains
encounter difficulties like outdated infrastructure, insufficient training, and
unreliable power. However, documented successes demonstrate that progress is
possible through integrated business approaches that embed innovations like
solar refrigeration and smart monitoring. As global health evolves, cold chain
systems must be redesigned to support emerging needs, including vaccine
development, biomanufacturing, and biobanking, and this needs to be looked at
through a One Health lens.
Course Type
Hybrid - Onsite & onlineDelivery Method
HybridGeneral enquiries
aces@cleancooling.org
Course Leader
Jean Pierre Musabyimana
Programme Dates
Course Fees
Attendance is currently FREE for all course
dates.
11th August - 5th September 2025
ACES
Rubirizi Campus, Kigali, Rwanda
- Apply
by email to aces-apply@cleancooling.org before 3rd
August 2025.
- Shortlisted
candidates will be notified by August 6th, 2025
- Onsite
(week 1 & 4) - ACES Rubirizi Campus, Kigali, Rwanda
- Online
sessions (week 2 & 3) - 3 hours a week, self-paced
Presenters: Jean Pierre Musabyimana
29th September - 24th October 2025
ACES
Rubirizi Campus, Kigali, Rwanda
- Apply
by email to aces-apply@cleancooling.org before 1st
September 2025.
- Shortlisted
candidates will be notified by September 15th, 2025
- Onsite
(week 1 & 4) - ACES Rubirizi Campus, Kigali, Rwanda
- Online
sessions (week 2 & 3) - 3 hours a week, self-paced
Presenters: Jean Pierre Musabyimana
Course Description
This course explores the critical role of cold chain systems
in global health, uniting disciplines such as supply chain management,
cryobiology, immunisation research, biobanking, pandemic surveillance,
regulatory science, and contextualised business model development. It is
tailored for professionals, researchers, students, and regulators working to
ensure the integrity of temperature-sensitive products like vaccines, reagents,
and biospecimens.
Participants will gain both theoretical knowledge and
hands-on skills to design, manage, and troubleshoot cold chain systems across
health, research, and outbreak response settings. Topics include temperature
effects on biological materials, infrastructure challenges, monitoring
technologies, and regulatory standards.
Using case studies such as COVID-19 and Ebola vaccine
distribution, the course underscores the life-saving importance of reliable
cold chain systems and addresses how cold chain failures contribute to vaccine
hesitancy. It discusses new generations of vaccines, such as mRNA vaccines
requiring optimal temperatures below 0 degrees, and how to design innovative
cold-chain systems for them. Additionally, it examines issues related to
cryogenic storage, biospecimen transportation mechanisms, and biobanking systems
needed for improved pandemic surveillance systems.
The course supports international compliance (ISO, WHO,
HACCP, etc.), enhances professional expertise, and aims to establish a
community of practice (CoP) in Rwanda and across Africa to foster innovation
and improve cold chain management for immunisation, nutrition, and health
security.
Who Should Apply
This course is open to a wide range of professionals,
students, experts and policy makers working at the intersection of health,
engineering, and biological sciences.
If you're committed to strengthening the integrity of
temperature-sensitive products in healthcare, research, and global public
health systems, this course is for you.
You are strongly encouraged to apply if you are:
- A
vaccine program manager, immunisation officer, or public health
practitioner
- A
laboratory technician, diagnostic specialist, or biobank coordinator
- A cold
chain engineer, refrigeration technician, or systems maintenance
specialist
- A
biomedical or electrical engineer involved in health-related
infrastructure
- A
logistics professional managing medical supply chains
- A
student or early-career professional in biology, biotechnology, veterinary
medicine, bioinformatics, engineering, or public health
- A
researcher in vaccine development, disease surveillance, diagnostic
innovation, or biospecimen management
- A
policymaker, health system planner, or regulatory officer overseeing
temperature-controlled health systems
- An
executive in the health system with a drive to develop efficient business
model to develop innovative solution in the public health supply
chain.
Whether you work in human or animal health, laboratory
systems, or supply chain logistics, this training provides the
interdisciplinary foundation needed to build sustainable and compliant cold
chain solutions.
Why This Course Matters
The increasing complexity of global health, the rise of
emerging diseases, and the expansion of biomanufacturing all demand stronger
cold chain systems.
In low- and middle-income countries, outdated
infrastructure, unreliable power, and lack of skilled personnel put millions of
lives at risk.
This course responds to those challenges by:
- Offering
real-world training rooted in the needs of LMICs
- Bridging
the gap between biological sciences and refrigeration engineering
- Showcasing
solutions like solar-powered cooling, smart monitoring, and regional
innovations such as Rwanda’s VaccAir and biobanking programs
- Laying
the groundwork for a Community of Practice (CoP) to
strengthen cold chain management in Global Health
What You Will Learn
By the end of the course, participants will be able to:
- Explain
how temperature affects the integrity of vaccines, reagents, and
biospecimens at the molecular level
- Describe
the full architecture of cold chain systems, including storage, transport,
monitoring, and validation
- Evaluate
different designs and needs for implemention of reliable cold chain
systems tailored to specific products and local contexts
- Identify
risk factors and troubleshoot failures in real-time, using digital tools
and emerging technologies
- Understand
the needed level pf compliancy with international regulatory frameworks
(e.g., WHO, ISO, GxP) to support quality assurance systems
- Apply
best practices from global case studies, including COVID-19, Ebola, and
malaria vaccine delivery, and utilise innovative cold-chain systems in
biomanufacturing as well as outbreak preparedness and response in your own
work.
- Learn
different collaborative strategies that link health, engineering,
logistics, and research through a One Health approach.
Syllabus Outline
Module 1: Foundations of Cold Chain Systems in Global
Health and Biological Integrity
- Definitions,
key components, and objectives of cold chain systems
- Importance
of preserving vaccine potency and diagnostic reliability
- Temperature
effects on biological products at cellular and molecular levels
- Degradation
mechanisms and preservation techniques (e.g., cryopreservation,
lyophilisation)
- Estimating
Remaining Shelf-Life (RSL) for foodstuffs, vaccines, and pharmaceuticals
- Overview
of logistics: storage, transport, and temperature monitoring
- Emerging
technologies: IoT, telemetry, blockchain, and innovative packaging
Module 2: Biospecimen and Diagnostics Cold Chain –
Management for Surveillance and Outbreak Control
- Packaging
and transport solutions: active systems (refrigerated trucks, cargo units)
vs. passive systems (insulated containers, phase-change materials)
- Infrastructure
needs and real-world deployment for static and mobile cryogenic storage
- Use
cases in national testing, surveillance, and emergency response programs
Module 3: Vaccine Cold Chain – Risk Management,
Challenges, and Innovations in Immunisation Programs
- Cold
chain requirements for different vaccine types
- Barriers:
infrastructure gaps, unreliable energy, and a limited trained workforce
- Innovations:
solar-powered units, passive cooling technologies, and new logistics
models
- Case
studies: COVID-19 and malaria vaccine delivery strategies
- Hands-on
exercises to evaluate and optimize vaccine cold chain conditions
Module 4: Nutrition and Nutritional Safety – The Role of
Cold Chain in Food Security and Health
- Nutrient
retention and degradation of perishable foods under different temperature
conditions
- Food
safety: controlling microbial growth and applying HACCP in food cold
chains
- Cold
chain in nutrition programs: maternal/child nutrition, school feeding,
emergency response
- Integration
with health systems: co-distribution of vaccines and therapeutic foods
- Technologies:
innovative packaging, solar cooling, cold rooms, and IoT for fortified
foods, RUTFs, and produce
- Addressing
LMIC challenges: spoilage reduction, infrastructure, and energy solutions;
case examples from Africa.
Module 5: Designing and Stress Testing Cold Chain Systems
– Case Studies and One Health Applications
- Practical
simulations and projects to design, monitor, and troubleshoot cold chain
systems
- Context-specific
applications: immunisation programs, insulin delivery, outbreak response
- Case
studies from Rwanda and other resource-limited settings
- Stress
testing cold chains under emergency conditions (e.g., disasters,
epidemics)
- Policies,
regulations, and quality standards: ISO, WHO, CDC, GxP, HACCP compliance
- Certification,
audits, and implementation of best practices
- Equity
and inclusion in cold chain access and decision-making
- Introduction
to action research and quality improvement for cold chain in global health
- Funding
mechanisms: public financing, concessional loans, international
partnerships
- Business
models for sustainable cooling: role of global initiatives in mobilising
finance and training
How To Apply
Interested applicants must submit a single PDF document
containing the following:
- A
cover letter addressed to the Academic Head, ACES, explaining your
motivation for attending the training
- A
detailed Curriculum Vitae (CV)
- Short
responses (max 150 words each) to the following questions:
- Do
you have any background in using cold chains? If yes, please describe.
- How
are you planning to implement the course-gained learning to change your
current practices?
- Are
there any potential barriers that may hinder your participation in this
training? (This will be kept confidential and used to facilitate your
participation.)
NOTE: ACES gives equal opportunities to people with
different backgrounds and genders.
Interested and qualified candidates should submit their
applications online by the designated deadline to ACES through aces-apply@cleancooling.org,
with the subject line:
" Cold Chain for Global Health – [Your Name]"
Join us in advancing your cold-chain for global health
skills with the course!
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